32.1.267 UncompetitiveInhibition2

Function

\[V_{0}=\frac{V_{\max}}{\frac{K_{m}}{S}+1} \qquad K_{ap}=K_{i}\left(\frac{K_{m}}{S}+1\right)\]

\[y=\frac{V_{0}}{2E}\left(E-x-K_{ap}+\sqrt{\left(E-x-K_{ap}\right)^{2}+4EK_{ap}}\right)\]

Brief Description

Tight-binding uncompetitive inhibition model describing the response to substrate concentration.

Sample Curve

Parameters

Number: 5

Names: Vmax, Km, Ki, E, I

Meanings: none

Lower Bounds: Vmax > 0, Km > 0, Ki > 0, E > 0, I (none)

Upper Bounds: none

Script Access

nlf_UncompetitiveInhibition2(x,Vmax,Km,Ki,E,I)

Function File

UncompetitiveInhibition2.fdf

Category

Enzyme Kinetics 2