32.1.266 UncompetitiveInhibition

Function

\[V_{0}=\frac{V_{\max}}{\frac{K_{m}}{S}+1} \qquad K_{ap}=K_{i}\left(\frac{K_{m}}{S}+1\right)\]

\[y=\frac{V_{0}}{2E}\left(E-x-K_{ap}+\sqrt{\left(E-x-K_{ap}\right)^{2}+4EK_{ap}}\right)\]

Brief Description

Tight-binding uncompetitive inhibition model.

Sample Curve

Parameters

Number: 5

Names: Vmax, Km, Ki, E, S

Meanings: none

Lower Bounds: Vmax > 0, Km > 0, Ki > 0, E > 0, S (none)

Upper Bounds: none

Script Access

nlf_UncompetitiveInhibition(x,Vmax,Km,Ki,E,S)

Function File

UncompetitiveInhibition.fdf

Category

Enzyme Kinetics 2