32.1.259 TightInhib

1 Function
2 Brief Description
3 Sample Curve
4 Parameters
5 Script Access
6 Function File
7 Category

Function

\[y=V\left( -\frac{E_t + K_i(S/K_m + 1) + x - \sqrt{-4E_t x + (E_t + K_i(S/K_m + 1) + x)^2}}{2E_t} + 1\right)\]

Brief Description

Morrison equation for tight binding inhibitors.

Sample Curve

Parameters

Number: 5

Names: V, Et, Ki, S, Km

Meanings: V = Enzyme velocity in the absence of inhibitor, Et = Enzyme concentration, Ki = Dissocation constant of inhibitor, S = Substrate concentration, Km = Michealis-Menten constant of enzyme

Lower Bounds: none

Upper Bounds: none

Script Access

nlf_TightInhib(x,V,Et,Ki,S,Km)

Function File

TightInhib.fdf