32.1.184 OperationalDepletionLog

1 Function
2 Brief Description
3 Sample Curve
4 Parameters
5 Derived Parameters
6 Script Access
7 Function File
8 Category

Function

\(y =B+\frac{Em-B}{op+1} \)

\(\text{where} \; op = \left(\frac{10^{\text{logKa}} + 10^x}{10^{\text{logtau} + x}}\right)^n \)

Brief Description

Operational model for receptor depletion with log(X)

Sample Curve

Parameters

Number: 5

Names: logKa, logtau, n, B, Em

Meanings: logKa=log of receptor dissociation constant, logtau=log of transducer constant tau, n=Transducer slope, B=Response in absence of agonist, Em=Maximum response

Lower Bounds: none

Upper Bounds: none

Derived Parameters

Ka=10^logKa

Tau=10^logtau

Script Access

nlf_OperationalDepletionLog(x,logKa,logtau,n,B,Em)

Function File

OperationalDepletionLog.fdf