32.1.179 OneSiteHomologous

Function

\[Bottom = NS \cdot HotnM\]

\(KdNM = 10^{logKD + 9}\)

\(ColdNM = 10^{x + 9}\)

\(y = Bottom + \frac{Bmax \cdot HotnM}{HotnM + ColdNM + KdNM}\)

Brief Description

One site homologous binding model with identical hot and cold ligand affinities.

Sample Curve

Parameters

Number: 4

Names: logKd, Bmax, NS, HotnM

Meanings: logKd=log10 Kd, Bmax=maximum receptor binding, NS=nonspecific binding fraction, HotnM=Hot ligand

Lower Bounds: none

Upper Bounds: none

Derived Parameters

Kd=10^(logKd)

Bottom=NS*HotnM

Script Access

nlf_OneSiteHomologous(x,logKd,Bmax,NS,HotnM)

Function File

OneSiteHomologous.fdf

Category

Binding