32.1.167 NoncompetitiveInhibition2

Contents

Function

\[v_{0}=\frac{V_{\max}\cdot x}{K_{m}+x}\]

\[y=\frac{v_{0}}{2E}\left((E-I-K_{i})+\sqrt{\left(E-I-K_{i}\right)^{2}+4EK_{i}}\right)\]

Brief Description

Tight-binding noncompetitive inhibition model describing the kinetic response to substrate concentration.

Sample Curve

NoncompetitiveInhibition2 Function.png

Parameters

Number: 5

Names: Vmax, Km, Ki, E, I Meanings: none

Lower Bounds: Vmax > 0, Km > 0, Ki > 0, E > 0 , I (none)

Upper Bounds: none

Script Access

nlf_NoncompetitiveInhibition2(x,Vmax,Km,Ki,E,I)

Function File

NoncompetitiveInhibition2.fdf

Category

Enzyme Kinetics 2