32.1.150 MichaelisMenten

Function

\[y=\frac{V_{max}x}{K_m+x}\]

Brief Description

Michaelis Menten function to describe relation of concentration of substrate and enzyme velocity.

Sample Curve

Parameters

Number: 2

Names: Vmax, Km

Meanings: Vmax = Maximum Velocity, Km = Michaelis Constant

Lower Bounds: Vmax > 0.0, Km > 0.0

Upper Bounds: none

Derived Parameters

The concentration for 10% response: EC10=Km/9

The concentration for 20% response: EC20=Km/4

The concentration for half-way response: EC50=Km

The concentration for 80% response: EC80=4*Km

The concentration for 90% response: EC90=9*Km

Script Access

nlf_MichaelisMenten(x,Vmax,Km)

Function File

FITFUNC\MichaelisMenten.FDF

Category

Growth/Sigmoidal, Pharmacology