32.1.57 EC50Shift
Contents
Function
\[y = Bt+\frac{Tp-Bt}{1+\left(\frac{EC50\times r}{x}\right)^s} \]
Brief Description
Allosteric EC50 shift when X is concentration or dose.
Sample Curve
Parameters
Number: 5
Names:Bt, Tp, EC50, r, s
Meanings: Bt=bottom asymptote, Tp=top asymptote, EC50=EC50 for agonist, r=EC50 ratio, s=Hill slope
Lower Bounds: none
Upper Bounds: none
Derived Parameters
logEC50=log(EC50)
Script Access
nlf_EC50Shift(x,Bt,Tp,EC50,r,s)
Function File
EC50Shift.fdf
Category
Dose Response