32.1.32 CompetitiveInhibition2

Function

\[V_0= \frac{V_{max}}{\frac {K_m}{x}+1} \]

\[K_ap = K_i \left( \frac{x}{K_m} + 1 \right)\]

\[y = \frac{V_0}{2E} \left( E- I- K_{ap} + \sqrt{(E-I-K_{ap})^2+4EK_{ap}} \right)\]

Brief Description

Tight-binding competitive inhibition model for high-affinity inhibitors with the substrate concentration as the primary independent variable

Sample Curve

Parameters

Number: 5

Names: Vmax, Km, Ki, E, I

Meanings: none

Lower Bounds: Vmax > 0, Km > 0, Ki > 0, E > 0

Upper Bounds: none

Script Access

nlf_CompetitiveInhibition2(x,Vmax,Km,Ki,E,I)

Function File

CompInhibition2.fdf

Category

Enzyme Kinetics 2