32.1.31 CompetitiveInhibition

Function

\[V_0= \frac{V_{max}}{\frac {K_m}{S}+1} \]

\[K_ap = K_i \left( \frac{S}{K_m} + 1 \right)\]

\[y = \frac{V_0}{2E} \left( E- x- K_{ap} + \sqrt{(E-x-K_{ap})^2+4EK_{ap}} \right)\]

Brief Description

Tight-binding competitive inhibition model for high-affinity inhibitors

Sample Curve

Parameters

Number: 5

Names: Vmax, Km, Ki, E, S

Meanings: none

Lower Bounds: Vmax > 0, Km > 0, Ki > 0, E > 0

Upper Bounds: none

Script Access

nlf_CompetitiveInhibition(x,Vmax,Km,Ki,E,S)

Function File

CompInhibition.fdf

Category

Enzyme Kinetics 2