32.1.1 AbsoluteIC50

Contents

Function

\(y = Bt+\frac{Tp-Bt}{1+\left(\frac{Tp-Bt}{fifty-Bt}-1\right)\left(\frac{AbsIC50}{x}\right)^s} \)

\(where \space fifty = \frac{Tp+B}{2}\)

Brief Description

Fit the absolute IC50.

Sample Curve

AbsoluteIC50.png

Parameters

Number: 5

Names: B, Bt, Tp, AbsIC50, s

Meanings: B= baseline, Bt=bottom asymptote, Tp=top asymptote, AbsIC50=absolute IC50, s=Hill slope

Lower Bounds: none

Upper Bounds: none

Derived Parameters

logAbsIC50=log(AbsIC50)

Script Access

nlf_AbsoluteIC50(x,B,Bt,Tp,AbsIC50,s)

Function File

AbsoluteIC50.fdf

Category

Dose Response